I am interested in RNA maturation,
RNA-protein interactions, in the structure of these associations, and
their function in bacteria and yeast.
Selected publications
- Time-resolved NMR monitoring of tRNA maturation: Abstract, Free full text
P. Barraud, A. Gato, M. Heiss, M. Catala, S. Kellner & C. Tisné
Nature Communications 10 (2019), 3373.
- To Be or Not to Be Modified: Miscellaneous Aspects Influencing Nucleotide Modifications in tRNAs: Abstract, Free full text
P. Barraud & C. Tisné
IUBMB Life 71 (2019), pp. 1126-1140.
- Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7: Abstract, Free full text
I. Beusch, P. Barraud, A. Moursy, A. Cléry & F.H.-T. Allain
eLife (2017), pp. 1226-1232.
- Functions of double-stranded RNA-binding domains in nucleocytoplasmic transport: Abstract, Full text, PDF
S. Banerjee & P. Barraud
RNA Biol. 111 (2014), pp. 1226-1232.
- A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1: Abstract, Free full text
P. Barraud, S. Banerjee, W.I. Mohamed, M.F. Jantsch & F.H.-T. Allain
Proc. Natl. Acad. Sci. USA. 111 (2014), pp. E1852-1861.
- Solution structure of the two RNA recognition motifs of hnRNP A1 using segmental isotope labeling: how the relative orientation between RRMs influences the nucleic acid binding topology: Abstract, Full text
P. Barraud & F.H.-T. Allain
J. Biomol. NMR 55 (2013), pp. 119-138.
- RNA recognition by double-stranded RNA binding domains: a matter of shape and sequence: Abstract, Full text
G. Masliah, P. Barraud & F.H.-T. Allain
Cell. Mol. Life Sci. 70 (2013), pp. 1875-1895.
- A strong 13C chemical shift signature provides the coordination mode of histidines in zinc-binding proteins: Abstract, Full text, PDF
P. Barraud, M. Schubert & F.H.-T. Allain
J. Biomol. NMR 53 (2012), pp. 93-101.
- RNAi keeps Atf1-bound stress response genes in check at nuclear pores: Abstract, Full text
K.J. Woolcock, R. Stunnenberg, D. Gaidatzis, H.-R. Hotz, S. Emmerth, P. Barraud & M. Bühler
Genes & Development 26 (2012), pp. 683-692.
- Solution structure of the N-terminal dsRBD of Drosophila ADAR and interaction studies
with RNA: Abstract, Full text
P. Barraud, B.S. Heale, M.A. O’Connell & F.H.-T. Allain
Biochimie 94 (2012), pp. 1499-1509.
- ADAR Proteins: double-stranded RNA and Z-DNA binding domains: Abstract, Full text
P. Barraud & F.H.-T. Allain
Curr. Top. Microbiol. Immunol. 353 (2012), pp. 35-60.
- An extended dsRBD with a novel zinc-binding motif mediates nuclear retention of fission yeast Dicer: Abstract, Free full text, PDF
P. Barraud, S. Emmerth, Y. Shimada, H.-R. Hotz, F.H.-T. Allain & M. Bühler
The EMBO Journal 30 (2011),
pp. 4223-4235.
- A unique conformation of the anticodon stem-loop
is associated with the capacity of tRNAfMet
to initiate protein synthesis: Abstract, Free
full text
P. Barraud, E. Schmitt, Y. Mechulam, F. Dardel & C.
Tisné
Nucleic Acids Res. 36 (2008),
pp. 4894-4901.
- Crystal structure of Thermus thermophilus tRNA m1A58
methyltransferase and biophysical characterization of its interaction
with tRNA: Abstract, Full text
P. Barraud, B. Golinelli-Pimpaneau, C. Atmanene, S. Sanglier, A. Van
Dorsselaer, L. Droogmans, F. Dardel & C. Tisné
J.
Mol. Biol. 377 (2008),
pp. 535-550.
- New insights into the formation of HIV-1 reverse
transcription initiation complex: Abstract, Full text
P. Barraud, C. Gaudin, F. Dardel & C. Tisné
Biochimie 89 (2007),
pp. 1204-1210.
Research
- Habilitation HDR « Biogenesis, structure and interactions of RNAs »
HDR defended on the 29th of June 2020.
- Post doctoral research
NMR structural study of the mechanism of action of hnRNP A1 in the regulation of alternative splicing;
Investigation of differents dsRBDs involved in sub-cellular localization and in nucleo-cytoplasmic shuttling.
Research conducted at the ETH Zurich, in the group of Frédéric Allain.
- Thesis « Structural study of different biological processes involving tRNA »
Thesis conducted at the Laboratoire
de cristallographie et RMN
biologiques, under the supervision of
Frédéric Dardel
and Carine Tisné at the University
Paris Descartes and defended on the 17th of July 2008.
Personal Data
Laboratoire d'expression génétique microbienne (UMR 8261)
Institut de biologie physico-chimique (IBPC)
13 rue Pierre et Marie Curie
75005 Paris
France
Email: pierre dot
barraud AT
ibpc dot
fr
Web:
http://barraud.pierre.free.fr/ and http://www.ibpc.fr/UMR8261/equipeTisne/HomeTisne.htm
Personal page: http://barraud.pierre.free.fr/perso/
last update: September 2020